IL-4 and IL-13 induce protection from complement and melittin in endothelial cells despite initial loss of cytoplasmic proteins: Membrane resealing impairs quantifying cytotoxicity with the lactate dehydrogenase permeability assay

BACKGROUND: Endothelial cell activation and injury by the terminal pathway of complement is important in various pathobiological processes, including xenograft rejection. Protection against injury by human complement can be induced in porcine endothelial cells (ECs) with IL-4 and IL-13 through metab...

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Détails bibliographiques
Publié dans:Xenotransplantation
Auteurs principaux: Benson, Barbara A., Vercellotti, Gregory M., Dalmasso, Agustin P.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519407/
https://ncbi.nlm.nih.gov/pubmed/26031609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12172
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