S100A14, a Member of the EF-hand Calcium-binding Proteins, Is Overexpressed in Breast Cancer and Acts as a Modulator of HER2 Signaling

HER2 is overexpressed in 20–25% of breast cancers. Overexpression of HER2 is an adverse prognostic factor and correlates with decreased patient survival. HER2 stimulates breast tumorigenesis via a number of intracellular signaling molecules, including PI3K/AKT and MAPK/ERK. S100A14, one member of th...

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Autors principals: Xu, Chengshan, Chen, Hongyan, Wang, Xiang, Gao, Jidong, Che, Yiqun, Li, Yi, Ding, Fang, Luo, Aiping, Zhang, Shuguang, Liu, Zhihua
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887208/
https://ncbi.nlm.nih.gov/pubmed/24285542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.469718
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