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Crystallization and calcium/sulfur SAD phasing of the human EF-hand protein S100A2

Human S100A2 is an EF-hand protein and acts as a major tumour suppressor, binding and activating p53 in a Ca(2+)-dependent manner. Ca(2+)-bound S100A2 was crystallized and its structure was determined based on the anomalous scattering provided by six S atoms from methionine residues and four calcium...

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Detalhes bibliográficos
Main Authors: Koch, Michael, Diez, Joachim, Wagner, Armin, Fritz, Günter
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935220/
https://ncbi.nlm.nih.gov/pubmed/20823519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110030691
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