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Phospholipase D(2) Mediates Survival Signaling through Direct Regulation of Akt in Glioblastoma Cells
The lack of innovative drug targets for glioblastoma multiforme (GBM) limits patient survival to approximately 1 year following diagnosis. The pro-survival kinase Akt provides an ideal target for the treatment of GBM as Akt signaling is frequently activated in this cancer type. However, the central...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887188/ https://ncbi.nlm.nih.gov/pubmed/24257753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.532978 |
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