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3,4-Methylenedioxy-β-nitrostyrene Inhibits NLRP3 Inflammasome Activation by Blocking Assembly of the Inflammasome

The NLRP3 inflammasome is a critical component of the innate immune system. NLRP3 activation is induced by diverse stimuli associated with bacterial infection or tissue damage, but its inappropriate activation is involved in the pathogenesis of inherited and acquired inflammatory diseases. However,...

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Sonraí Bibleagrafaíochta
Main Authors: He, Yuan, Varadarajan, Saranyaraajan, Muñoz-Planillo, Raúl, Burberry, Aaron, Nakamura, Yuumi, Núñez, Gabriel
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887181/
https://ncbi.nlm.nih.gov/pubmed/24265316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515080
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