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3,4-Methylenedioxy-β-nitrostyrene Inhibits NLRP3 Inflammasome Activation by Blocking Assembly of the Inflammasome

The NLRP3 inflammasome is a critical component of the innate immune system. NLRP3 activation is induced by diverse stimuli associated with bacterial infection or tissue damage, but its inappropriate activation is involved in the pathogenesis of inherited and acquired inflammatory diseases. However,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: He, Yuan, Varadarajan, Saranyaraajan, Muñoz-Planillo, Raúl, Burberry, Aaron, Nakamura, Yuumi, Núñez, Gabriel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887181/
https://ncbi.nlm.nih.gov/pubmed/24265316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515080
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