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Polarity and Charge of the Periplasmic Loop Determine the YidC and Sec Translocase Requirement for the M13 Procoat Lep Protein

During membrane biogenesis, the M13 procoat protein is inserted into the lipid bilayer in a strictly YidC-dependent manner with both the hydrophobic signal sequence and the membrane anchor sequence promoting translocation of the periplasmic loop via a hairpin mechanism. Here, we find that the transl...

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Detalhes bibliográficos
Main Authors: Soman, Raunak, Yuan, Jijun, Kuhn, Andreas, Dalbey, Ross E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887171/
https://ncbi.nlm.nih.gov/pubmed/24275657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.522250
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