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Trends in drug delivery through tissue barriers containing tight junctions
A limitation in the uptake of many drugs is the restricted permeation through tissue barriers. There are two general ways to cross barriers formed by cell layers: by transcytosis or by diffusion through the intercellular space. In the latter, tight junctions (TJs) play the decisive role in the regul...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887097/ https://ncbi.nlm.nih.gov/pubmed/24665392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/tisb.24565 |
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