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Fate of Lymphocytes after Withdrawal of Tofacitinib Treatment

Tofacitinib (Tofa) is an inhibitor of Janus Kinase 3, developed for the treatment of autoimmune diseases and for the prevention of transplant rejection. Due to its selective action on proliferating cells, Tofa can offer a way to block T cell activation, without toxic effects on resting cells. Howeve...

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Main Authors: Piscianz, Elisa, Valencic, Erica, Cuzzoni, Eva, De Iudicibus, Sara, De Lorenzo, Elisa, Decorti, Giuliana, Tommasini, Alberto
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887061/
https://ncbi.nlm.nih.gov/pubmed/24416411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085463
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