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Fate of Lymphocytes after Withdrawal of Tofacitinib Treatment

Tofacitinib (Tofa) is an inhibitor of Janus Kinase 3, developed for the treatment of autoimmune diseases and for the prevention of transplant rejection. Due to its selective action on proliferating cells, Tofa can offer a way to block T cell activation, without toxic effects on resting cells. Howeve...

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Autors principals: Piscianz, Elisa, Valencic, Erica, Cuzzoni, Eva, De Iudicibus, Sara, De Lorenzo, Elisa, Decorti, Giuliana, Tommasini, Alberto
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887061/
https://ncbi.nlm.nih.gov/pubmed/24416411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085463
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