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Effect of Wild-Type Shigella Species and Attenuated Shigella Vaccine Candidates on Small Intestinal Barrier Function, Antigen Trafficking, and Cytokine Release

Bacterial dysentery due to Shigella species is a major cause of morbidity and mortality worldwide. The pathogenesis of Shigella is based on the bacteria's ability to invade and replicate within the colonic epithelium, resulting in severe intestinal inflammatory response and epithelial destructi...

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Detalhes bibliográficos
Main Authors: Fiorentino, Maria, Levine, Myron M., Sztein, Marcelo B., Fasano, Alessio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887025/
https://ncbi.nlm.nih.gov/pubmed/24416363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085211
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