T cell mediated immunity induced by the live-attenuated Shigella flexneri 2a vaccine candidate CVD 1208S in humans

BACKGROUND: Shigellosis persists as a public health problem worldwide causing ~ 165,000 deaths every year, of which ~ 55,000 are in children less than 5 years of age. No vaccine against shigellosis is currently licensed. The live-attenuated Shigella flexneri 2a vaccine candidate CVD 1208S (S. flexne...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Toapanta, Franklin R., Bernal, Paula J., Kotloff, Karen L., Levine, Myron M., Sztein, Marcelo B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851169/
https://ncbi.nlm.nih.gov/pubmed/29534721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1439-1
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