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Regulation of acrAB expression by cellular metabolites in Escherichia coli

OBJECTIVES: Multidrug efflux pumps mediate resistance to antibiotics and other toxic compounds. We studied the role of AcrAB-TolC, the main efflux pump in Escherichia coli, in regulating gene expression. METHODS: Deletion mutants, an acrABp-lacZ fusion and reverse transcription–real-time quantitativ...

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Detalhes bibliográficos
Main Authors: Ruiz, Cristian, Levy, Stuart B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886929/
https://ncbi.nlm.nih.gov/pubmed/24043404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt352
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