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MMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC
Multiple myeloma (MM) represents the malignant proliferation of terminally differentiated B cells, which, in many cases, is associated with the maintenance of high levels of the oncoprotein c-MYC. Overexpression of the histone methyltransferase MMSET (WHSC1/NSD2), due to t(4;14) chromosomal transloc...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3886861/ https://ncbi.nlm.nih.gov/pubmed/22972034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.269 |
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