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c-Myc modulates microRNA processing via the transcriptional regulation of Drosha

The c-Myc oncogenic transcription factor is known to regulate microRNA (miRNA) expression at the transcriptional level. However, little is known about the function of c-Myc in miRNA processing. Here, we report that Drosha, one of the most important components of the miRNA processing machinery, is a...

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Detalhes bibliográficos
Main Authors: Wang, Xingwu, Zhao, Xiaocheng, Gao, Ping, Wu, Mian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672885/
https://ncbi.nlm.nih.gov/pubmed/23735886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01942
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