Activation of Hypoxia‐Inducible Factor‐2 in Adipocytes Results in Pathological Cardiac Hypertrophy

BACKGROUND: Obesity can cause structural and functional abnormalities of the heart via complex but largely undefined mechanisms. Emerging evidence has shown that obesity results in reduced oxygen concentrations, or hypoxia, in adipose tissue. We hypothesized that the adipocyte hypoxia‐signaling path...

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Detalhes bibliográficos
Main Authors: Lin, Qun, Huang, Yan, Booth, Carmen J., Haase, Volker H., Johnson, Randall S., Celeste Simon, M., Giordano, Frank J., Yun, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886757/
https://ncbi.nlm.nih.gov/pubmed/24326162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000548
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