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An Epigenetic “LINK(RNA)” to Pathological Cardiac Hypertrophy

Reinduction of fetal gene expression is characteristic of the failing adult heart. Han et al. (2014) demonstrate that a novel cluster of long noncoding RNAs, Myheart, protects the heart from pathological hypertrophy, involving a negative-feedback molecular circuit with the epigenetic Brg1 complex to...

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Publicat a:Cell Metab
Autors principals: Liu, Jianming, Wang, Da-Zhi
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886471/
https://ncbi.nlm.nih.gov/pubmed/25295782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.09.011
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