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Effects of Notch signaling on regulation of myeloid cell differentiation in cancer

Functionally altered myeloid cells play an important role in immune suppression in cancer, in angiogenesis, and in tumor cells’ invasion and metastases. Here, we report that inhibition of Notch signaling in hematopoietic progenitor cells (HPC), myeloid-derived suppressor cells (MDSC), and dendritic...

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Autors principals: Cheng, Pingyan, Kumar, Vinit, Liu, Hao, Youn, Je-In, Fishman, Mayer, Sherman, Simon, Gabrilovich, Dmitry
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886562/
https://ncbi.nlm.nih.gov/pubmed/24220241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1686
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