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Effects of Notch signaling on regulation of myeloid cell differentiation in cancer

Functionally altered myeloid cells play an important role in immune suppression in cancer, in angiogenesis, and in tumor cells’ invasion and metastases. Here, we report that inhibition of Notch signaling in hematopoietic progenitor cells (HPC), myeloid-derived suppressor cells (MDSC), and dendritic...

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Detalhes bibliográficos
Main Authors: Cheng, Pingyan, Kumar, Vinit, Liu, Hao, Youn, Je-In, Fishman, Mayer, Sherman, Simon, Gabrilovich, Dmitry
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886562/
https://ncbi.nlm.nih.gov/pubmed/24220241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1686
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