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Methylated Messenger RNA Synthesis In Vitro by Purified Reovirus

Purified human reovirus contains RNA methylase activity in addition to an RNA polymerase. Virions incubated under appropriate conditions in the presence of S-adenosyl-L-methionine synthesize mRNA that is specifically methylated in the 5′-terminal guanosine. Alkaline digestion of the methylated RNA r...

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Pubblicato in:Proc Natl Acad Sci U S A
Autore principale: Shatkin, Aaron J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1974
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388651/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4528644/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.8.3204
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