Methylated Messenger RNA Synthesis In Vitro by Purified Reovirus
Purified human reovirus contains RNA methylase activity in addition to an RNA polymerase. Virions incubated under appropriate conditions in the presence of S-adenosyl-L-methionine synthesize mRNA that is specifically methylated in the 5′-terminal guanosine. Alkaline digestion of the methylated RNA r...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1974
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388651/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4528644/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.8.3204 |
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