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5′-Guanylylimidodiphosphate, A Potent Activator of Adenylate Cyclase Systems in Eukaryotic Cells

5′-Guanylylimidodiphosphate (Gpp(NH)-p) stimulates adenylate cyclase [ATP-pyrophosphate-lyase (cyclizing), EC 4.6.1.1] activity in plasma membranes isolated from frog and salmon erythrocytes, from rat adrenal, hepatic, and fat cells, and from bovine thyroid cells. The nucleotide acts cooperatively w...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Londos, Constantine, Salomon, Yoram, Lin, Michael C., Harwood, James P., Schramm, Michael, Wolff, J., Rodbell, Martin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1974
Fag:
Biological Sciences: Biochemistry
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388626/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4607368/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.8.3087
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