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IGF-2 mediates intestinal mucosal hyperplasia in retinoblastoma protein (Rb)-deficient mice

PURPOSE: We have previously demonstrated a hyperplastic phenotype when Rb expression was disrupted within the intestinal epithelium. These findings mimic resection-induced adaptation suggesting a possible mechanistic role for Rb during adaptation. The purpose of the present study was to elucidate a...

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Bibliographic Details
Main Authors: Choi, Pamela, Guo, Jun, Erwin, Christopher R., Warner, Brad W.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885982/
https://ncbi.nlm.nih.gov/pubmed/23845628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2013.03.042
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