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Mutation profiling identifies numerous rare drug targets and distinct mutation patterns in different clinical subtypes of breast cancers

The mutation pattern of breast cancer molecular subtypes is incompletely understood. The purpose of this study was to identify mutations in genes that may be targeted with currently available investigational drugs in the three major breast cancer subtypes (ER+/HER2−, HER2+, and Triple Negative). We...

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Huvudupphovsmän: Santarpia, Libero, Qi, Yuan, Stemke-Hale, Katherine, Wang, Bailiang, Young, Elliana J., Booser, Daniel J., Holmes, Frankie A., O’Shaughnessy, Joyce, Hellerstedt, Beth, Pippen, John, Vidaurre, Tatiana, Gomez, Henry, Valero, Vicente, Hortobagyi, Gabriel N., Symmans, W. Fraser, Bottai, Giulia, Di Leo, Angelo, Gonzalez-Angulo, Ana M., Pusztai, Lajos
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885980/
https://ncbi.nlm.nih.gov/pubmed/22538770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2035-3
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