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Increased Thermal Stability of Chromatin Containing 5-Bromodeoxyuridine-Substituted DNA

The replacement of thymidine by 5-bromodeoxyuridine in DNA leads to a greatly enhanced stability of chromatin from hepatoma tissue culture or embryonic rat pancreas, as measured by thermal chromatography on hydroxylapatite. The increased stability is directly correlated with the degree of bromodeoxy...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: David, John, Gordon, Joel S., Rutter, William J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1974
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388561/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4368811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.7.2808
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