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Increased Thermal Stability of Chromatin Containing 5-Bromodeoxyuridine-Substituted DNA

The replacement of thymidine by 5-bromodeoxyuridine in DNA leads to a greatly enhanced stability of chromatin from hepatoma tissue culture or embryonic rat pancreas, as measured by thermal chromatography on hydroxylapatite. The increased stability is directly correlated with the degree of bromodeoxy...

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Bibliographic Details
Main Authors: David, John, Gordon, Joel S., Rutter, William J.
Format: Artigo
Language:Inglês
Published: 1974
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC388561/
https://ncbi.nlm.nih.gov/pubmed/4368811
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