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Combining Chemoinformatics with Bioinformatics: In Silico Prediction of Bacterial Flavor-Forming Pathways by a Chemical Systems Biology Approach “Reverse Pathway Engineering”

The incompleteness of genome-scale metabolic models is a major bottleneck for systems biology approaches, which are based on large numbers of metabolites as identified and quantified by metabolomics. Many of the revealed secondary metabolites and/or their derivatives, such as flavor compounds, are n...

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Autors principals: Liu, Mengjin, Bienfait, Bruno, Sacher, Oliver, Gasteiger, Johann, Siezen, Roland J., Nauta, Arjen, Geurts, Jan M. W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885609/
https://ncbi.nlm.nih.gov/pubmed/24416282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084769
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