Apoptosis and APC in colorectal tumorigenesis.
Tumors result from disruptions in the homeostatic mechanisms that regulate cell birth and cell death. In colon cancer, one of the earliest manifestation of this imbalance is the formation of polyps, caused by somatic and inherited mutations of the adenomatous polyposis coli (APC) tumor suppressor ge...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1996
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.15.7950 |
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