NPPB and ACAN, Two Novel SHOX2 Transcription Targets Implicated in Skeletal Development

SHOX and SHOX2 transcription factors are highly homologous, with even identical homeodomains. Genetic alterations in SHOX result in two skeletal dysplasias; Léri-Weill dyschondrosteosis (LWD) and Langer mesomelic dysplasia (LMD), while no human genetic disease has been linked to date with SHOX2. SHO...

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Bibliografiska uppgifter
Huvudupphovsmän: Aza-Carmona, Miriam, Barca-Tierno, Veronica, Hisado-Oliva, Alfonso, Belinchón, Alberta, Gorbenko-del Blanco, Darya, Rodriguez, Jose Ignacio, Benito-Sanz, Sara, Campos-Barros, Angel, Heath, Karen E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885427/
https://ncbi.nlm.nih.gov/pubmed/24421874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083104
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