Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling

The gut microbiota is a complex ecosystem that has coevolved with host physiology. Colonization of germ-free (GF) mice with a microbiota promotes increased vessel density in the small intestine(1), but little is known about the mechanisms involved. Tissue factor (TF) is the membrane receptor that in...

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Main Authors: Reinhardt, Christoph, Bergentall, Mattias, Greiner, Thomas U., Schaffner, Florence, Östergren-Lundén, Gunnel, Petersen, Lars C., Ruf, Wolfram, Bäckhed, Fredrik
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885420/
https://ncbi.nlm.nih.gov/pubmed/22407318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10893
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