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Pharmacokinetics, Brain Delivery, and Efficacy in Brain Tumor-Bearing Mice of Glutathione Pegylated Liposomal Doxorubicin (2B3-101)

Brain cancer is a devastating disease affecting many people worldwide. Effective treatment with chemotherapeutics is limited due to the presence of the blood-brain barrier (BBB) that tightly regulates the diffusion of endogenous molecules but also xenobiotics. Glutathione pegylated liposomal doxorub...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Gaillard, Pieter J., Appeldoorn, Chantal C. M., Dorland, Rick, van Kregten, Joan, Manca, Francesca, Vugts, Danielle J., Windhorst, Bert, van Dongen, Guus A. M. S., de Vries, Helga E., Maussang, David, van Tellingen, Olaf
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885379/
https://ncbi.nlm.nih.gov/pubmed/24416140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082331
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