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Selective Toxicity of Diphtheria Toxin for Malignant Cells

Purified diphtheria toxin is shown to inhibit protein synthesis in Ehrlich-Lettré ascites carcinoma cells in vitro. Protein synthesis in Ehrlich-Lettré cells is at least 10,000 times more sensitive to toxin than protein synthesis in normal mouse spleen or thymus cells. This sensitivity correlates wi...

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Bibliografiske detaljer
Main Authors: Iglewski, Barbara H., Rittenberg, Marvin B.
Format: Artigo
Sprog:Inglês
Udgivet: 1974
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC388537/
https://ncbi.nlm.nih.gov/pubmed/4527970
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