Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice

OBJECTIVE: Humanin (HN) is a cytoprotective peptide derived from endogenous mitochondria, expressed in the endothelial layer of human vessels, but its role in atherogenesis in vivo is not known. In vitro study, however, HN reduced oxidized low-density lipoprotein induced formation of reactive oxygen...

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Bibliografski detalji
Glavni autori: Oh, Yun K., Bachar, Adi R., Zacharias, David G., Kim, Sung Gyun, Wan, Junxiang, Cobb, Laura J., Lerman, Lilach O., Cohen, Pinchas, Lerman, Amir
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885346/
https://ncbi.nlm.nih.gov/pubmed/21763658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2011.06.038
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