Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice

AIMS: Humanin (HN) is endogenous mitochondrial-derived cytoprotective peptide that has shown protective effects against atherosclerosis and is expressed in human vessels. However, its effects on the progression of kidney disease are unknown. We hypothesized that HN would protect the kidney in the ea...

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Detalhes bibliográficos
Main Authors: Zhang, Xin, Urbieta-Caceres, Victor H., Eirin, Alfonso, Bell, Caitlin C., Crane, John A., Tang, Hui, Jordan, Kyra, Oh, Yun-Kyu, Zhu, Xiang-Yang, Korsmo, Michael J., Bachar, Adi R., Cohen, Pinchas, Lerman, Amir, Lerman, Lilach O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703734/
https://ncbi.nlm.nih.gov/pubmed/22820173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.07.010
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