Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice

AIMS: Humanin (HN) is endogenous mitochondrial-derived cytoprotective peptide that has shown protective effects against atherosclerosis and is expressed in human vessels. However, its effects on the progression of kidney disease are unknown. We hypothesized that HN would protect the kidney in the ea...

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Main Authors: Zhang, Xin, Urbieta-Caceres, Victor H., Eirin, Alfonso, Bell, Caitlin C., Crane, John A., Tang, Hui, Jordan, Kyra, Oh, Yun-Kyu, Zhu, Xiang-Yang, Korsmo, Michael J., Bachar, Adi R., Cohen, Pinchas, Lerman, Amir, Lerman, Lilach O.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703734/
https://ncbi.nlm.nih.gov/pubmed/22820173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.07.010
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