Curcumin Pretreatment Induces Nrf2 and an Antioxidant Response and Prevents Hemin-Induced Toxicity in Primary Cultures of Cerebellar Granule Neurons of Rats

Curcumin is a bifunctional antioxidant derived from Curcuma longa. This study identifies curcumin as a neuroprotectant against hemin-induced damage in primary cultures of cerebellar granule neurons (CGNs) of rats. Hemin, the oxidized form of heme, is a highly reactive compound that induces cellular...

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Detalhes bibliográficos
Main Authors: González-Reyes, Susana, Guzmán-Beltrán, Silvia, Medina-Campos, Omar Noel, Pedraza-Chaverri, José
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885319/
https://ncbi.nlm.nih.gov/pubmed/24454990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/801418
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