Curcumin Induces Nrf2 Nuclear Translocation and Prevents Glomerular Hypertension, Hyperfiltration, Oxidant Stress, and the Decrease in Antioxidant Enzymes in 5/6 Nephrectomized Rats

Renal injury resulting from renal ablation induced by 5/6 nephrectomy (5/6NX) is associated with oxidant stress, glomerular hypertension, hyperfiltration, and impaired Nrf2-Keap1 pathway. The purpose of this work was to know if the bifunctional antioxidant curcumin may induce nuclear translocation o...

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Detalhes bibliográficos
Main Authors: Tapia, Edilia, Soto, Virgilia, Ortiz-Vega, Karla Mariana, Zarco-Márquez, Guillermo, Molina-Jijón, Eduardo, Cristóbal-García, Magdalena, Santamaría, José, García-Niño, Wylly Ramsés, Correa, Francisco, Zazueta, Cecilia, Pedraza-Chaverri, José
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424005/
https://ncbi.nlm.nih.gov/pubmed/22919438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/269039
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