High linear-energy-transfer radiation can overcome radioresistance of glioma stem-like cells to low linear-energy-transfer radiation

Ionizing radiation is applied as the standard treatment for glioblastoma multiforme (GBM). However, radiotherapy remains merely palliative, not curative, because of the existence of glioma stem cells (GSCs), which are regarded as highly radioresistant to low linear-energy-transfer (LET) photons. Her...

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Detalhes bibliográficos
Main Authors: Hirota, Yuki, Masunaga, Shin-Ichiro, Kondo, Natsuko, Kawabata, Shinji, Hirakawa, Hirokazu, Yajima, Hirohiko, Fujimori, Akira, Ono, Koji, Kuroiwa, Toshihiko, Miyatake, Shin-Ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885128/
https://ncbi.nlm.nih.gov/pubmed/23955054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrt095
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