High linear-energy-transfer radiation can overcome radioresistance of glioma stem-like cells to low linear-energy-transfer radiation

Ionizing radiation is applied as the standard treatment for glioblastoma multiforme (GBM). However, radiotherapy remains merely palliative, not curative, because of the existence of glioma stem cells (GSCs), which are regarded as highly radioresistant to low linear-energy-transfer (LET) photons. Her...

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Bibliografiske detaljer
Main Authors: Hirota, Yuki, Masunaga, Shin-Ichiro, Kondo, Natsuko, Kawabata, Shinji, Hirakawa, Hirokazu, Yajima, Hirohiko, Fujimori, Akira, Ono, Koji, Kuroiwa, Toshihiko, Miyatake, Shin-Ichi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885128/
https://ncbi.nlm.nih.gov/pubmed/23955054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrt095
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