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Demonstration of Dopamine-sensitive Adenylate Cyclase in Malignant Neuroblastoma Cells and Change in Sensitivity of Adenylate Cyclase to Catecholamines in “Differentiated” Cells

Adenylate cyclase (EC 4.6.1.1) activity was stimulated by low concentrations of dopamine and apomorphine, but not by low concentrations of norepinephrine in homogenates of malignant mouse neuroblastoma cells. In cyclic AMP-induced “differentiated” cells, dopamine concentration required for a maximal...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Prasad, Kedar N., Gilmer, Katrina N.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1974
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388492/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4366772/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.6.2525
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