Demonstration of Dopamine-sensitive Adenylate Cyclase in Malignant Neuroblastoma Cells and Change in Sensitivity of Adenylate Cyclase to Catecholamines in “Differentiated” Cells
Adenylate cyclase (EC 4.6.1.1) activity was stimulated by low concentrations of dopamine and apomorphine, but not by low concentrations of norepinephrine in homogenates of malignant mouse neuroblastoma cells. In cyclic AMP-induced “differentiated” cells, dopamine concentration required for a maximal...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1974
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4366772/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.6.2525 |
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