Chargement en cours...

G17-modified hammerhead ribozymes are active in vitro and in vivo

Natural hammerhead ribozymes (HHRz) feature tertiary interactions between hairpin loops or bulges in two of three helices that surround the catalytic core of conserved nucleotides. Their conservation was originally established on minimal versions lacking the tertiary interactions. While those sequen...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kalweit, Anne, Hammann, Christian
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884650/
https://ncbi.nlm.nih.gov/pubmed/24145822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.040543.113
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!