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G17-modified hammerhead ribozymes are active in vitro and in vivo

Natural hammerhead ribozymes (HHRz) feature tertiary interactions between hairpin loops or bulges in two of three helices that surround the catalytic core of conserved nucleotides. Their conservation was originally established on minimal versions lacking the tertiary interactions. While those sequen...

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Dades bibliogràfiques
Autors principals: Kalweit, Anne, Hammann, Christian
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884650/
https://ncbi.nlm.nih.gov/pubmed/24145822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.040543.113
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