Combining Molecular Targeted Drugs to Inhibit Both Cancer Cells and Activated Stromal Cells in Gastric Cancer

Recent studies have revealed that PDGF plays a role in promoting progressive tumor growth in several cancers, including gastric cancer. Cancer-associated fibroblasts, pericytes, and lymphatic endothelial cells in stroma express high levels of PDGF receptor (PDGF-R); cancer cells and vascular endothe...

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Bibliographic Details
Main Authors: Onoyama, Mieko, Kitadai, Yasuhiko, Tanaka, Yuichiro, Yuge, Ryo, Shinagawa, Kei, Tanaka, Shinji, Yasui, Wataru, Chayama, Kazuaki
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884530/
https://ncbi.nlm.nih.gov/pubmed/24403861
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