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Convergence of dopamine and glutamate signaling onto striatal ERK activation in response to drugs of abuse
Despite their distinct targets, all addictive drugs commonly abused by humans evoke increases in dopamine (DA) concentration within the striatum. The main DA Guanine nucleotide binding protein couple receptors (GPCRs) expressed by medium-sized spiny neurons of the striatum are the D1R and D2R, which...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3884214/ https://ncbi.nlm.nih.gov/pubmed/24409148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00172 |
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