Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum

Many drugs of abuse exert their addictive effects by increasing extracellular dopamine in the nucleus accumbens, where they likely alter the plasticity of corticostriatal glutamatergic transmission. This mechanism implies key molecular alterations in neurons in which both dopamine and glutamate inpu...

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Detalhes bibliográficos
Main Authors: Valjent, Emmanuel, Pascoli, Vincent, Svenningsson, Per, Paul, Surojit, Enslen, Hervé, Corvol, Jean-Christophe, Stipanovich, Alexandre, Caboche, Jocelyne, Lombroso, Paul J., Nairn, Angus C., Greengard, Paul, Hervé, Denis, Girault, Jean-Antoine
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544317/
https://ncbi.nlm.nih.gov/pubmed/15608059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408305102
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