CYP2B6*6 is associated with increased breast cancer risk

The cytochrome P450 2B6 (CYP2B6) is involved in the metabolism of testosterone. Functional changes in this enzyme may influence endogenous hormone exposure, which has been associated with risk of breast cancer. To assess potential associations between two functional polymorphisms CYP2B6_516_G>T (...

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Main Authors: Justenhoven, Christina, Pentimalli, Daniela, Rabstein, Sylvia, Harth, Volker, Lotz, Anne, Pesch, Beate, Brüning, Thomas, Dörk, Thilo, Schürmann, Peter, Bogdanova, Natalia, Park-Simon, Tjoung-Won, Couch, Fergus J., Olson, Janet E., Fasching, Peter A, Beckmann, Matthias W., Häberle, Lothar, Ekici, Arif, Hall, Per, Czene, Kamilla, Liu, Janjun, Li, Jingmei, Baisch, Christian, Hamann, Ute, Ko, Yon-Dschun, Brauch, Hiltrud
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883876/
https://ncbi.nlm.nih.gov/pubmed/23824676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28356
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