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Clinical Relevance of CYP2D6 Genetics for Tamoxifen Response in Breast Cancer
Tamoxifen is a standard endocrine therapy for the prevention and treatment of steroid hormone receptor-positive breast cancer. Tamoxifen requires enzymatic activation by CYP 450 enzymes for the formation of clinically relevant metabolites, 4-OH-tamoxifen and endoxifen, which both have a greater affi...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
S. Karger GmbH
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2931018/ https://ncbi.nlm.nih.gov/pubmed/20824020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000114642 |
| Etiketak: |
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