Methylation loss at H19 imprinted gene correlates withmethylenetetrahydrofolate reductase gene promoter hypermethylation in semen samples from infertile males

Aberrant methylation at the H19 paternal imprinted gene has been identified in different cohorts of infertile males. The causes of H19 methylation errors are poorly understood. In this study, we investigated the methylation status of the H19 gene in semen DNA samples from infertile males affected by...

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Autors principals: Rotondo, John C, Selvatici, Rita, Di Domenico, Maura, Marci, Roberto, Vesce, Fortunato, Tognon, Mauro, Martini, Fernanda
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883776/
https://ncbi.nlm.nih.gov/pubmed/23975186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.25798
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