SERPINA1 Gene Promoter Is Differentially Methylated in Peripheral Blood Mononuclear Cells of Pregnant Women

SERine Protein INhibitor-A1 (SERPINA1) is an inducible blood cell gene coding for alpha1-antitrypsin (AAT), a plasma protease inhibitor whose circulating levels are raised during inflammation, infection and advanced pregnancy. DNA methylation has been suggested to play a role in SERPINA1 gene expres...

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Publicat a:Front Cell Dev Biol
Autors principals: Rotondo, John Charles, Oton-Gonzalez, Lucia, Selvatici, Rita, Rizzo, Paola, Pavasini, Rita, Campo, Gianluca Calogero, Lanzillotti, Carmen, Mazziotta, Chiara, De Mattei, Monica, Tognon, Mauro, Martini, Fernanda
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494783/
https://ncbi.nlm.nih.gov/pubmed/33015055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.550543
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