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The Enzymatic Release of O(6)-methylguanine and 3-methyladenine from DNA Reacted with the Carcinogen N-methyl-N-nitrosourea

Endonuclease II (deoxyribonucleate oligonucleotidohydrolase, EC 3.1.4.30) of Escherichia coli has been shown to break phosphodiester bonds in alkylated DNA and depurinated DNA. The hypothesis that depurination is a step in the mechanism of the reaction with alkylated DNA is supported by in vitro exp...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Kirtikar, D. M., Goldthwait, D. A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1974
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388377/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4600266/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.5.2022
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